Learning objectives and clinical implications
- Develops the ability to suspect JSLE in children and adolescents with unexplained multisystem symptoms.
- Encourages thorough family history taking to identify genetic and autoimmune predisposition.
- Improves recognition of key clinical signs such as malar rash, arthritis, nephritis, and neuropsychiatric symptoms.
- Reinforces the importance of simple investigations like urine analysis for early detection of renal involvement.
- Highlights the need for considering neurological and psychiatric assessment in children with seizures or behavioral changes.
- Strengthens the use of autoantibody testing and complement levels in confirming diagnosis and monitoring disease.
- Prepares students to understand treatment challenges in children, including drug toxicity, growth impact, and adherence issues.
- Emphasizes the importance of multidisciplinary, long-term follow-up to reduce morbidity and improve outcomes in JSLE patients.