General Medicine
Cancer-associated fibroblast–treg cell crosstalk in lung adenocarcinoma: emerging mechanisms and therapeutic implications
Introduction The tumor microenvironment (TME) is a highly complex and dynamic ecosystem comprising malignant cells, stromal cells, extracellular matrix (ECM), and diverse immune-cell populations. Increasing evidence indicates that interactions between these cellular compartments are critical determinants of tumor progression, immune…
Dermatology
Case Discussion
Radiology
Advancing hearing loss diagnosis: OCT imaging now targets the inner ear
Researchers have successfully adapted optical coherence tomography (OCT), a technology commonly used to visualize eye structures, for imaging the inner ear. This innovative adaptation enables clinicians to measure fluid levels…
New MRI technology offers superior diagnosis for aortic stenosis
Scientists at the University of East Anglia (UEA) have developed a cutting-edge MRI-based technique that significantly improves the diagnosis and management of aortic stenosis, a life-threatening heart condition affecting hundreds…
Quiz
Crystal arthropathy gout
Test your knowledge of gout and calcium pyrophosphate deposition (CPPD) disease with this clinical quiz! From needle-shaped, negatively birefringent monosodium urate crystals to rhomboid, positively birefringent CPP crystals, challenge yourself…
News & Perspectives
Obstetrics & Gynecology
Tryptophan metabolism emerges as a key regulator of female reproductive health
Tryptophan metabolism emerges as a key regulator of female reproductive health A new review published in the Chinese Medical Journal has highlighted the potentially important role of tryptophan metabolism in female reproductive health, extending beyond its traditional association with fertility. The review,…